I hadn't had my oral appliance professionally cleaned in at least 18 months. I had been using liquid Hand soap. But after ONE 15-minute soak in Dr. Berland's Cleanadent Liquid Crystals Oral Appliance Cleanser, it was almost perfectly clean! I highly recommend this product!
I have a dental appliance for sleep apnea and this is a great product for keeping it clean. I also use it on my retainers, and it brightens them up much better than any of the tablets that dissolve.